HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Methylthiazol-2-yl)ethanamine → N-((9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)methyl)-2-(4-methylthiazol-2-yl)ethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Methylthiazol-2-yl)ethanamine | HCID 3422636 | — |
| Reactant | 2-(2-methylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purine-8-carbaldehyde | HCID 59605420 | — |
| Product | N-((9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purin-8-yl)methyl)-2-(4-methylthiazol-2-yl)ethanamine | HCID 59605467 | — |
Reaction Steps
Following General Procedure L for reductive amination, 9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-6-morpholino-9H-purine-8-carbaldehyde and 2-(4-methylthiazol-2-yl)ethanamine were reacted to give 321. [M+H]+ 504.6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173650B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-7ec28c21dce247bf9d59c59c2919b149 |
| Source note | uspto-grants-2012_05 |