HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylbenzimidazole → HCID 59605255, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylbenzimidazole | HCID 11984 | — |
| Reactant | HCID 87421174 | HCID 87421174 | — |
| Product | HCID 59605255 | HCID 59605255 | — |
Reaction Steps
Following General Procedure I for Buchwald coupling, 2-methylbenzimidazole and racemic 4-(2-chloro-8-((hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)methyl)-9-methyl-9H-purin-6-yl)morpholine were reacted. The enantiomers were separated by SFC to give 415. LCMS m/z: 488.2 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173650B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-ac371531f3a54d0abae719cbd5f1ad0b |
| Source note | uspto-grants-2012_05 |