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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1923164Generated: November 2, 2026

Benzimidazole → HCID 59605403, compound

https://huagongshe.com/reaction/1923164

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzimidazoleHCID 5798—
ReactantDifluoroacetic acidHCID 9788—
Reactant4-(8-((4-tert-butylpiperazin-1-yl)methyl)-2-chloro-9-methyl-9H-purin-6-yl)morpholineHCID 59605470—
ProductHCID 59605403HCID 59605403—

Reaction Steps

Following General Procedure J for Multi-Step Benzimidazole formation, 4-(8-((4-tert-butylpiperazin-1-yl)methyl)-2-chloro-9-methyl-9H-purin-6-yl)morpholine was converted to 463 with difluoroacetic acid. LCMS: M+H+=554.3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173650B2
Source datasetuspto-grants-2012_05
ORD IDord-8070ae2c932544a9844bc245def810a2
Source noteuspto-grants-2012_05