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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1923174Generated: October 25, 2026

Benzimidazole → HCID 59605565, compound

https://huagongshe.com/reaction/1923174

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzimidazoleHCID 5798—
ReactantDifluoroacetic acidHCID 9788—
Reactant2-(4-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperazin-1-yl)-2-methylpropan-1-olHCID 86648251—
ProductHCID 59605565HCID 59605565—

Reaction Steps

Following General Procedure J for Multi-Step Benzimidazole formation, 2-(4-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperazin-1-yl)-2-methylpropan-1-ol was converted to 473 with difluoroacetic acid. LCMS: M+H+=570.3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173650B2
Source datasetuspto-grants-2012_05
ORD IDord-161e8b17a9904cd4be3585ec8e89d325
Source noteuspto-grants-2012_05