HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl vinyl sulfone → 4-(9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-((1-(2-(methylsulfonyl)ethyl)azetidin-3-yl)methyl)-9H-purin-6-yl)morpholine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl vinyl sulfone | HCID 19354 | — |
| Edukt | 8-Azetidin-3-ylmethyl-2-(2-methylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purine | HCID 59605459 | — |
| Produkt | 4-(9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-((1-(2-(methylsulfonyl)ethyl)azetidin-3-yl)methyl)-9H-purin-6-yl)morpholine | HCID 59606152 | — |
Reaktionsschritte
Following General Procedure C, 4-(8-(azetidin-3-ylmethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine and methylvinylsulfone were reacted to give 543. LCMS m/z: 525.3 (MH+)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08173650B2 |
| Quelldatensatz | uspto-grants-2012_05 |
| ORD ID | ord-d77a12b3dcb74f778e3b07db4f297796 |
| Quellennotiz | uspto-grants-2012_05 |