HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopropanamide → HCID 59605858, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopropanamide | HCID 101118 | — |
| Reactant | 8-Azetidin-3-ylmethyl-2-(2-ethylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purine | HCID 59605281 | — |
| Product | HCID 59605858 | HCID 59605858 | — |
Reaction Steps
Following General Procedure C, 4-(8-(azetidin-3-ylmethyl)-2-(2-ethyl-1H-benzo[d]imidazol-1-yl)-9-methyl-9H-purin-6-yl)morpholine and 2-bromopropionamide were reacted to give a racemic mixture. The enantiomers were separated by SFC to give 546. LCMS m/z: 252.7 (2M+H+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173650B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-3a2d96f3073745e5a91aee1830d19366 |
| Source note | uspto-grants-2012_05 |