HRID1923262

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3530572

1-tert-butylpiperazine

C8H18N2

结构：CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C(=O)O)n(C)c2n1

HCID59605325

未命名化合物

PRODUCTS

生成物

结构：CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C(=O)N3CCN(C(C)(C)C)CC3)n(C)c2n1

HCID59605490

未命名化合物

PROCEDURE

实验过程

Following General Procedure K, 2-(2-Ethyl-1H-benzo[d]imidazol-1-yl)-9-methyl-6-morpholino-9H-purine-8-carboxylic acid was coupled with 1-tert-butylpiperazine according to General Procedure K to give 567. LCMS m/z: 266.7 (2M+H+)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1b981e89b86240f6b2c805c1eb54a784
来源数据集: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08173650B2
来源说明: uspto-grants-2012_05

反应 SMILES

[CH2:1]([C:3]1[N:7]([C:8]2[N:16]=[C:15]3[C:11]([N:12]=[C:13]([C:18](O)=[O:19])[N:14]3[CH3:17])=[C:10]([N:21]3[CH2:26][CH2:25][O:24][CH2:23][CH2:22]3)[N:9]=2)[C:6]2[CH:27]=[CH:28][CH:29]=[CH:30][C:5]=2[N:4]=1)[CH3:2].[C:31]([N:35]1[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]1)([CH3:34])([CH3:33])[CH3:32]>>[C:31]([N:35]1[CH2:40][CH2:39][N:38]([C:18]([C:13]2[N:14]([CH3:17])[C:15]3[C:11]([N:12]=2)=[C:10]([N:21]2[CH2:22][CH2:23][O:24][CH2:25][CH2:26]2)[N:9]=[C:8]([N:7]2[C:6]4[CH:27]=[CH:28][CH:29]=[CH:30][C:5]=4[N:4]=[C:3]2[CH2:1][CH3:2])[N:16]=3)=[O:19])[CH2:37][CH2:36]1)([CH3:34])([CH3:33])[CH3:32]