HRID1923275

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID287560

2-bromo-n,2-dimethylpropanamide

C5H10BrNO

反应SMILES：Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CNC3)n(C)c2n1

HCID59605459

未命名化合物

PRODUCTS

产物

反应SMILES：CNC(=O)C(C)(C)N1CC(Cc2nc3c(N4CCOCC4)nc(-n4c(C)nc5ccccc54)nc3n2C)C1

HCID59605417

未命名化合物

PROCEDURE

实验过程

Following General Procedure C, 4-(8-(azetidin-3-ylmethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine and 2-bromo-N,2-dimethylpropanamide were reacted to give 580. LCMS m/z: 259.7 (2M+H+)

WORKUP

后处理

customwere reacted

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-54f21939b65a49e9b0c45dd46623fd49
来源数据集: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US08173650B2
来源说明: uspto-grants-2012_05

反应SMILES

[NH:1]1[CH2:4][CH:3]([CH2:5][C:6]2[N:7]([CH3:31])[C:8]3[C:13]([N:14]=2)=[C:12]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)[N:11]=[C:10]([N:21]2[C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=4[N:23]=[C:22]2[CH3:30])[N:9]=3)[CH2:2]1.Br[C:33]([CH3:39])([CH3:38])[C:34]([NH:36][CH3:37])=[O:35]>>[CH3:37][NH:36][C:34](=[O:35])[C:33]([CH3:39])([N:1]1[CH2:2][CH:3]([CH2:5][C:6]2[N:7]([CH3:31])[C:8]3[C:13]([N:14]=2)=[C:12]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)[N:11]=[C:10]([N:21]2[C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=4[N:23]=[C:22]2[CH3:30])[N:9]=3)[CH2:4]1)[CH3:38]