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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1923431Generated: November 4, 2026

Methylamine → HCID 67521373, compound

https://huagongshe.com/reaction/1923431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantHCID 86632759HCID 86632759—
SolventMethanolHCID 887—
ProductHCID 67521373HCID 67521373—

Reaction Steps

15 mg (0.061 mmol) N-[4-(2-Amino-4-methylpyrimidin-6-yloxymethyl)-benzyl]-2,2,2-trifluoro-acetamide is dissolved in 1 mL methanol and treated with 2 mL methylamine (33% in ethanol). The reaction mixture is stirred at room temperature over night and all volatiles are removed in vacuo. The product is used without further purification in the next step. ESI-MS m/z 245.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178314B2
Source datasetuspto-grants-2012_05
ORD IDord-840d12a7c0e743f3a1fadf6fad9e4b56
Source noteuspto-grants-2012_05