HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 67521373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 86632759 | HCID 86632759 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 67521373 | HCID 67521373 | — |
Reaction Steps
15 mg (0.061 mmol) N-[4-(2-Amino-4-methylpyrimidin-6-yloxymethyl)-benzyl]-2,2,2-trifluoro-acetamide is dissolved in 1 mL methanol and treated with 2 mL methylamine (33% in ethanol). The reaction mixture is stirred at room temperature over night and all volatiles are removed in vacuo. The product is used without further purification in the next step. ESI-MS m/z 245.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178314B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-840d12a7c0e743f3a1fadf6fad9e4b56 |
| Source note | uspto-grants-2012_05 |