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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1923524Generated: November 2, 2026

Cyclopropylamine → HCID 59568487, compound

https://huagongshe.com/reaction/1923524

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
ReactantHCID 66643777HCID 66643777—
ProductHCID 59568487HCID 5956848782%

Reaction Steps

As described for example 31b, 2-{2-[3-(5-fluoro-pyridin-2-yl)-5-methyl-isoxazol-4-yl]-ethyl}-4-methyl-thiazole-5-carboxylic acid (69 mg, 0.20 mmol) was converted, using cyclopropylamine instead of 4-aminotetrahydropyran, to the title compound (63 mg, 82%) which was obtained as an off white solid. MS: m/e=387.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178522B2
Source datasetuspto-grants-2012_05
ORD IDord-c3c6afeb948749f38f7cf0dc4c1d96c9
Source noteuspto-grants-2012_05