HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → HCID 59568487, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | HCID 66643777 | HCID 66643777 | — |
| Product | HCID 59568487 | HCID 59568487 | 82% |
Reaction Steps
As described for example 31b, 2-{2-[3-(5-fluoro-pyridin-2-yl)-5-methyl-isoxazol-4-yl]-ethyl}-4-methyl-thiazole-5-carboxylic acid (69 mg, 0.20 mmol) was converted, using cyclopropylamine instead of 4-aminotetrahydropyran, to the title compound (63 mg, 82%) which was obtained as an off white solid. MS: m/e=387.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178522B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-c3c6afeb948749f38f7cf0dc4c1d96c9 |
| Source note | uspto-grants-2012_05 |