Methylamine → HCID 59568532, compound

Participants

Reaction Steps

As described for example 31b, 2-{2-[3-(5-fluoro-pyridin-2-yl)-5-methyl-isoxazol-4-yl]-ethyl}-4-methyl-thiazole-5-carboxylic acid (69 mg, 0.20 mmol) was converted, using methylamine (2M solution in THF) instead of 4-aminotetrahydropyran, to the title compound (34 mg, 47%) which was obtained as an off white solid. MS: m/e=361.2 [M+H]+.

Provenance & Evidence