HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → HCID 59568511, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | HCID 66643727 | HCID 66643727 | — |
| Product | HCID 59568511 | HCID 59568511 | 51% |
Reaction Steps
As described for example 40c, 2-{2-[3-(5-fluoro-pyridin-2-yl)-5-methyl-isoxazol-4-yl]-ethyl}-thiazole-5-carboxylic acid (67 mg, 0.20 mmol) was converted, using isopropylamine instead of 4-aminotetrahydropyran, to the title compound (42 mg, 51%) which was obtained as a white solid. MS: m/e=375.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178522B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-1b945a53090b4c43ad1a037c1ee658f3 |
| Source note | uspto-grants-2012_05 |