Methylamine → HCID 49782711, compound

Participants

Reaction Steps

As described for example 40c, 2-{2-[3-(5-fluoro-pyridin-2-yl)-5-methyl-isoxazol-4-yl]-ethyl}-thiazole-5-carboxylic acid (67 mg, 0.20 mmol) was converted, using methylamine (2M solution in THF) instead of 4-aminotetrahydropyran, to the title compound (33 mg, 48%) which was obtained as a white solid. MS: m/e=347.0 [M+H]+.

Provenance & Evidence