HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Alaninol → HCID 66643782, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Alaninol | HCID 80307 | — |
| Reactant | 2-[2-(3-Butyl-5-methyl-isoxazol-4-yl)-ethyl]-4-methyl-thiazole-5-carboxylic acid methyl ester | HCID 66643681 | — |
| Product | HCID 66643782 | HCID 66643782 | 71% |
Reaction Steps
As described for example 53, 2-[2-(3-butyl-5-methyl-isoxazol-4-yl)-ethyl]-4-methyl-thiazole-5-carboxylic acid methyl ester (100 mg, 0.31 mmol) was converted, using L-alaninol instead of 2-amino-1,3-propandiol, to the title compound (80 mg, 71%) which was obtained as an off white oil. MS: m/e=366.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178522B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-466481dedf3a43849ecbbb63df7b1f42 |
| Source note | uspto-grants-2012_05 |