Sodium Carbonate → HCID 25012075, compound

Participants

Reaction Steps

The sulphonamide from example 2 (1.0 eq), 4-fluorophenylboronic acid and Pd(PPh3)4 were dissolved in dioxane (3 mL/mmol) and an aqueous solution of sodium carbonate (2 mL/mmol) was added. The reaction mixture was heated under reflux overnight and after completion of the reaction the solvent was removed under reduced pressure. The residue was purified by chromatography to yield the title compound as beige solid.

Provenance & Evidence