Pyrrolidine → HCID 67521418, compound

Participants

Reaction Conditions

Reaction Steps

3-Amino-2-thioxo-2,3-dihydro-1H-quinazolin-4-one (0.200 g, 1.04 mmol) was dissolved in pyrrolidine (0.850 mL, 10.4 mmol) and the mixture was heated at 150° C. for 20 minutes under microwave conditions. After cooling the mixture was diluted with water and extracted with EtOAc. The combined organics were washed with water and brine, dried (Na2SO4) and evaporated in vacuo to give the title compound (0.180 g, 75%).

Provenance & Evidence