HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 44221300, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | Benzoic acid, 2-isothiocyanato-, methyl ester | HCID 85243 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 44221300 | HCID 44221300 | 91.5% |
Reaction Steps
Methyl 2-isothiocyanatobenzoate (3.37 g, 17.4 mmol) was dissolved in THF (75 mL), followed by addition of diethylamine (3.59 mL, 34.9 mmol). The reaction mixture was stirred at RT. After 1 h the mixture was poured into water (400 mL). The formed precipitate was collected by filtration, washed with water and dried in vacuo to give pure title compound (4.24 g, 91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178544B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-36ea97196f414aaca840e89da06bce12 |
| Source note | uspto-grants-2012_05 |