反应详情

To a solution of 3.5 g (18.1 mM) of N-(cyclopropylmethyl)-3-nitropyridin-2-amine in 36 ml of methanol, were added 700 mg of palladium on carbon at 5%. The reaction mixture was stirred for 3 h at room temperature under hydrogen atmosphere at room pressure. The catalyst was filtrated on Celite and the filtrate was evaporated under vacuum to give 3.1 g of N2-(cyclopropylmethyl)pyridine-2,3-diamine as a solid. Yield: 99.5%.

1. filtrationThe catalyst was filtrated on Celite
2. customthe filtrate was evaporated under vacuum