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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924490Generated: October 26, 2026

2,5-Difluorophenylhydrazine → 3-[2-(2,5-Difluoro-phenyl)-2H-pyrazol-3-yl]-1-phenyl-1H-pyridazin-4-one

https://huagongshe.com/reaction/1924490

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DifluorophenylhydrazineHCID 588957—
Reactant(E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-oneHCID 12742246—
Product3-[2-(2,5-Difluoro-phenyl)-2H-pyrazol-3-yl]-1-phenyl-1H-pyridazin-4-oneHCID 4621945224%

Reaction Steps

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-phenyl-1H-pyridazin-4-one (A-1) and 2,5-difluorophenylhydrazine according to the method described for Example 1 in 24% yield. MS: M=351.1 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-a11a27f083fc430588beac3c78ea61f2
Source noteuspto-grants-2012_05