HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-one → 3-[2-(2-Methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-1-phenyl-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-one | HCID 12742246 | — |
| Reactant | 4-Hydrazino-2-methylpyridine | HCID 20073663 | — |
| Product | 3-[2-(2-Methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-1-phenyl-1H-pyridazin-4-one | HCID 46219576 | 37% |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-phenyl-1H-pyridazin-4-one (A-1) and 4-hydrazino-2-methylpyridine according to the method described for Example 1 in 37% yield. MS: M=330.1 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-ebb898057300449dab9b47e5152a4d93 |
| Source note | uspto-grants-2012_05 |