(E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-one → HCID 46219575, compound

HRID 1924504Notes

Reaction equation

HRID 1924504 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:8]=1)=O.[Cl:21][C:22]1[CH:27]=[C:26]([NH:28]N)[CH:25]=[CH:24][N:23]=1>>[Cl:21][C:22]1[CH:27]=[C:26]([N:28]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:2]2)[CH:25]=[CH:24][N:23]=1

Participants

3

Reactant 2

HCID 12742246(E)-3-(3-(Dimethylamino)acryloyl)-1-phenylpyridazin-4(1H)-oneHCID 211064422-Chloro-4-hydrazinylpyridine

Product 1

HCID 46219575HCID 46219575, compoundYield 9%

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-phenyl-1H-pyridazin-4-one (A-1) and 2-chloro-4-hydrazinopyridine according to the method described for Example 1 in 9% yield. MS: M=350.1 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-5e1c954cc3374d82b92afa41d03611b2
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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