4-Hydrazinopyridine → HCID 46219694, compound

HRID 1924506Notes

Reaction equation

HRID 1924506 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=2)[N:8]=1)=O.[NH:26]([C:28]1[CH:33]=[CH:32][N:31]=[CH:30][CH:29]=1)N>>[N:31]1[CH:32]=[CH:33][C:28]([N:26]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:2]2)=[CH:29][CH:30]=1

Participants

3

Reactant 2

HCID 4166314-HydrazinopyridineHCID 593701233-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

Product 1

HCID 46219694HCID 46219694, compoundYield 16%

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and 4-hydrazinopyridine according to the method described for Example 1 in 16% yield. MS: M=400.2 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-63757f368ba64409b164cb790767f4b0
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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