(2,3-Dimethylphenyl)hydrazine → HCID 46220045, compound

HRID 1924527Notes

Reaction equation

HRID 1924527 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=2)[N:8]=1)=O.[CH3:26][C:27]1[C:32]([CH3:33])=[CH:31][CH:30]=[CH:29][C:28]=1[NH:34]N>>[CH3:26][C:27]1[C:32]([CH3:33])=[CH:31][CH:30]=[CH:29][C:28]=1[N:34]1[C:5]([C:7]2[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=3)[N:8]=2)=[CH:4][CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 2736278(2,3-Dimethylphenyl)hydrazineHCID 593701233-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

Product 1

HCID 46220045HCID 46220045, compound

Procedure

Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and (2,3-dimethyl-phenyl)-hydrazine according to example 43 gave the desired product. MS: M=425.8 (M)+

Sources & evidence

ORD record
ord-ed248516f9fe42e8b258de99e28d2005
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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