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4-Hydrazinobenzoic acid → 4-{5-[1-(3-Methanesulfonyl-phenyl)-4-oxo-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Hydrazinobenzoic acid | HCID 12089 | — |
| 反応物 | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one | HCID 59370171 | — |
| 生成物 | 4-{5-[1-(3-Methanesulfonyl-phenyl)-4-oxo-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-benzoic acid | HCID 46218950 | — |
反応手順
Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and 4-hydrazino-benzoic acid according to example 43 gave the desired product. MS: M=437.0 (M+H)+
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08178538B2 |
| 出典データセット | uspto-grants-2012_05 |
| ORD ID | ord-165c6ee4061745f7a705395f9d0426ca |
| 出典メモ | uspto-grants-2012_05 |