HCID 334419, compound → HCID 59370053, compound

HRID 1924550Notes

Reaction equation

HRID 1924550 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[NH:25]([C:27]1[N:34]=[C:33]([CH3:35])[CH:32]=[C:31]([CH3:36])[C:28]=1[C:29]#[N:30])N>>[CH3:23][S:20]([C:16]1[CH:15]=[C:14]([N:9]2[CH:10]=[CH:11][C:12](=[O:13])[C:7]([C:5]3[N:25]([C:27]4[N:34]=[C:33]([CH3:35])[CH:32]=[C:31]([CH3:36])[C:28]=4[C:29]#[N:30])[N:2]=[CH:3][CH:4]=3)=[N:8]2)[CH:19]=[CH:18][CH:17]=1)(=[O:22])=[O:21]

Participants

3

Reactant 2

HCID 334419HCID 334419, compoundHCID 593701713-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one

Product 1

HCID 59370053HCID 59370053, compound

Procedure

Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and 2-hydrazino-4,6-dimethyl-nicotinonitrile according to example 43 gave the desired product. MS: M=447.0 (M+H)+

Sources & evidence

ORD record
ord-023e9424e75e4939b6828c014e3aa987
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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