HCID 55279166, compound → HCID 59370107, compound

HRID 1924551Notes

Reaction equation

HRID 1924551 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[CH2:25]([O:27][C:28](=[O:37])[C:29]1[CH:34]=[CH:33][N:32]=[C:31]([NH:35]N)[CH:30]=1)[CH3:26]>>[CH2:25]([O:27][C:28](=[O:37])[C:29]1[CH:34]=[CH:33][N:32]=[C:31]([N:35]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:2]2)[CH:30]=1)[CH3:26]

Participants

3

Reactant 2

HCID 55279166HCID 55279166, compoundHCID 593701713-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one

Product 1

HCID 59370107HCID 59370107, compound

Procedure

Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and 2-hydrazino-isonicotinic acid ethyl ester according to example 43 gave the desired product. MS: M=466.0 (M+H)+

Sources & evidence

ORD record
ord-c6404798402743de8f24561d7853f001
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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