4-Hydrazinobenzonitrile → HCID 59370146, compound

HRID 1924553Notes

Reaction equation

HRID 1924553 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=2)[N:8]=1)=O.[NH:26]([C:28]1[CH:35]=[CH:34][C:31]([C:32]#[N:33])=[CH:30][CH:29]=1)N>>[O:13]=[C:12]1[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=2)[N:8]=[C:7]1[C:5]1[N:26]([C:28]2[CH:35]=[CH:34][C:31]([C:32]#[N:33])=[CH:30][CH:29]=2)[N:2]=[CH:3][CH:4]=1

Participants

3

Reactant 2

HCID 5837844-HydrazinobenzonitrileHCID 593701233-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

Product 1

HCID 59370146HCID 59370146, compound

Procedure

Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and 4-hydrazino-benzonitrile according to example 43 gave the desired product. MS: M=424.2 (M+H)+

Sources & evidence

ORD record
ord-766baa2460784ee0b04952acee829070
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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