HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14742847, compound → HCID 59369953, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14742847 | HCID 14742847 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one | HCID 59370123 | — |
| Product | HCID 59369953 | HCID 59369953 | — |
Reaction Steps
Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and 6-(4-hydrazino-phenyl)-4,5-dihydro-2H-pyridazin-3-one (described in Journal of Medicinal Chemistry (1990), 33(10), 2870-5) according to example 43 gave the desired product. MS: M=495.0 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-2fbe7ee5b15b4793b29fea172c52e77d |
| Source note | uspto-grants-2012_05 |