HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine, 1-naphthalenyl- → 3-(2-Naphthalen-1-yl-2H-pyrazol-3-yl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine, 1-naphthalenyl- | HCID 75240 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one | HCID 59370123 | — |
| Product | 3-(2-Naphthalen-1-yl-2H-pyrazol-3-yl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one | HCID 59369972 | — |
Reaction Steps
Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and naphthalen-1-yl-hydrazine according to example 43 gave the desired product. MS: M=449.0 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-70a79dac815940069ccafbb79a07e39e |
| Source note | uspto-grants-2012_05 |