HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-hydrazine → 3-[2-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-2H-pyrazol-3-yl]-1-(3-methanesulfonyl-phenyl)-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-hydrazine | HCID 5164485 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one | HCID 59370171 | — |
| Product | 3-[2-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-2H-pyrazol-3-yl]-1-(3-methanesulfonyl-phenyl)-1H-pyridazin-4-one | HCID 46218823 | — |
Reaction Steps
Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and (2,3-dihydro-benzo[1,4]dioxin-6-yl)-hydrazine according to example 43 gave the desired product. MS: M=451 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-f6526adee1d94ffd87c73ed80ab9ad8f |
| Source note | uspto-grants-2012_05 |