HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Fluorophenyl)hydrazine → 3-[2-(3-Fluoro-phenyl)-2H-pyrazol-3-yl]-1-(3-methanesulfonyl-phenyl)-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Fluorophenyl)hydrazine | HCID 581026 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one | HCID 59370171 | — |
| Product | 3-[2-(3-Fluoro-phenyl)-2H-pyrazol-3-yl]-1-(3-methanesulfonyl-phenyl)-1H-pyridazin-4-one | HCID 46218822 | — |
Reaction Steps
Reaction of 3-((E)-3-dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and (3-fluoro-phenyl)-hydrazine according to example 43 gave the desired product. MS: M=410.6 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-9445a38e24384bf2841d09c87803e877 |
| Source note | uspto-grants-2012_05 |