HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydrazinylbenzonitrile → 3-{5-[1-(3-Methanesulfonyl-phenyl)-4-oxo-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydrazinylbenzonitrile | HCID 1488145 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one | HCID 59370171 | — |
| Product | 3-{5-[1-(3-Methanesulfonyl-phenyl)-4-oxo-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-benzonitrile | HCID 59370152 | 61% |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and 3-hydrazino-benzonitrile according to the method described for Example 91 in 61% yield. MS: M=418.3 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-01f830b5b60743d3aa245d85d570a991 |
| Source note | uspto-grants-2012_05 |