HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Difluorophenylhydrazine → 3-{3-[2-(2,5-Difluoro-phenyl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-N,N-dimethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Difluorophenylhydrazine | HCID 588957 | — |
| Reactant | 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide | HCID 59370163 | — |
| Product | 3-{3-[2-(2,5-Difluoro-phenyl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-N,N-dimethyl-benzenesulfonamide | HCID 59370030 | — |
Reaction Steps
The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide (A-12) and 2,5-difluoro-phenylhydrazine according to the method described for example 91. MS: M=458.2 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-f39110386fcf4986ae2a67a40740b828 |
| Source note | uspto-grants-2012_05 |