2-Hydrazinylthiazole → HCID 59370062, compound
Reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[S:25]1[CH:29]=[CH:28][N:27]=[C:26]1[NH:30]N>>[CH3:23][S:20]([C:16]1[CH:15]=[C:14]([N:9]2[CH:10]=[CH:11][C:12](=[O:13])[C:7]([C:5]3[N:30]([C:26]4[S:25][CH:29]=[CH:28][N:27]=4)[N:2]=[CH:3][CH:4]=3)=[N:8]2)[CH:19]=[CH:18][CH:17]=1)(=[O:22])=[O:21]Participants
3
Procedure
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and thiazol-2-yl-hydrazine according to the method described for example 91. MS: M=400.1 (M+H)+
Workup
- customThe product was obtained
Sources & evidence
- ORD record
- ord-2cd7e6d84c77465791cc8aa4938d3cf4
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08178538B2
Reaction notes
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