4-Hydrazino-2-methylpyridine → 3-[2-(2-Methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

HRID 1924597노트

반응식

HRID 1924597 반응식
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=2)[N:8]=1)=O.[NH:26]([C:28]1[CH:33]=[CH:32][N:31]=[C:30]([CH3:34])[CH:29]=1)N>>[CH3:34][C:30]1[CH:29]=[C:28]([N:26]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:2]2)[CH:33]=[CH:32][N:31]=1

참가 물질

3

반응물 2

HCID 200736634-Hydrazino-2-methylpyridineHCID 593701233-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

생성물 1

HCID 593700193-[2-(2-Methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

실험 절차

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and 4-hydrazino-2-methylpyridine according to the method described for example 43. MS: M=414.2 (M+H)+

후처리

  1. customThe product was obtained

출처 및 근거

ORD 기록
ord-d2a057d3c4d44a868100481c27175cb0
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08178538B2

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