2,5-Difluorophenylhydrazine → HCID 59370100, compound

HRID 1924600Notes

Reaction equation

HRID 1924600 reaction equation
[F:1][C:2]1([F:25])[O:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([N:11]3[CH:16]=[CH:15][C:14](=[O:17])[C:13]([C:18](=O)/[CH:19]=[CH:20]/N(C)C)=[N:12]3)[C:4]=2[O:3]1.[F:26][C:27]1[CH:32]=[CH:31][C:30]([F:33])=[CH:29][C:28]=1[NH:34][NH2:35]>>[F:25][C:2]1([F:1])[O:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([N:11]3[CH:16]=[CH:15][C:14](=[O:17])[C:13]([C:18]4[N:34]([C:28]5[CH:29]=[C:30]([F:33])[CH:31]=[CH:32][C:27]=5[F:26])[N:35]=[CH:20][CH:19]=4)=[N:12]3)[C:4]=2[O:3]1

Participants

3

Reactant 2

HCID 5889572,5-DifluorophenylhydrazineHCID 593701341-(2,2-Difluoro-benzo[1,3]dioxol-4-yl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one

Product 1

HCID 59370100HCID 59370100, compound

Procedure

The product was obtained starting from 1-(2,2-Difluoro-benzo[1,3]dioxol-4-yl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one (A-15) and 2,5-difluoro-phenylhydrazine according to the method described for example 91. MS: M=431.2 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-6deb78af1c5847198a73cbb45d0506d2
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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