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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924603Generated: October 26, 2026

4-Hydrazino-2-methylpyridine → 3-[2-(2-Methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

https://huagongshe.com/reaction/1924603

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydrazino-2-methylpyridineHCID 20073663—
Reactant3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-oneHCID 59370034—
Product3-[2-(2-Methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-oneHCID 59370086—

Reaction Steps

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-8) and 4-hydrazino-2-methylpyridine according to the method described for example 91. MS: M=414.2 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-7acc64ce363145e7adb4d61261fefc06
Source noteuspto-grants-2012_05