4-Hydrazino-2-methylpyridine → N,N-Dimethyl-3-{3-[2-(2-methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-benzenesulfonamide

HRID 1924605Notes

Reaction equation

HRID 1924605 reaction equation
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:15]=[C:16]([S:20]([N:23]([CH3:25])[CH3:24])(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=2)[N:8]=1)=O.[NH:27]([C:29]1[CH:34]=[CH:33][N:32]=[C:31]([CH3:35])[CH:30]=1)[NH2:28]>>[CH3:24][N:23]([CH3:25])[S:20]([C:16]1[CH:17]=[CH:18][CH:19]=[C:14]([N:9]2[CH:10]=[CH:11][C:12](=[O:13])[C:7]([C:5]3[N:27]([C:29]4[CH:34]=[CH:33][N:32]=[C:31]([CH3:35])[CH:30]=4)[N:28]=[CH:3][CH:4]=3)=[N:8]2)[CH:15]=1)(=[O:22])=[O:21]

Participants

3

Reactant 2

HCID 200736634-Hydrazino-2-methylpyridineHCID 593701633-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide

Product 1

HCID 59369981N,N-Dimethyl-3-{3-[2-(2-methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-benzenesulfonamide

Procedure

The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide (A-12) and 4-hydrazino-2-methylpyridine according to the method described for example 91. MS: M=437.2 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-38854ec07af74c329e86b2920f0cd24e
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

Loading…