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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924610Generated: October 26, 2026

(4-Fluorophenyl)hydrazine → 3-[2-(4-Fluoro-phenyl)-2H-pyrazol-3-yl]-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

https://huagongshe.com/reaction/1924610

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Fluorophenyl)hydrazineHCID 69982—
Reactant3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-oneHCID 59370034—
Product3-[2-(4-Fluoro-phenyl)-2H-pyrazol-3-yl]-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-oneHCID 59370119—

Reaction Steps

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-8) and 4-fluoro-phenylhydrazine according to the method described for example 43. MS: M=417.1 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-59297a5410274154a40e7c3fcd2c8bf9
Source noteuspto-grants-2012_05