3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one → HCID 59369968, compound

HRID 1924619Notes

Reaction equation

HRID 1924619 reaction equation
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][C:17]([O:20][C:21]([F:24])([F:23])[F:22])=[CH:16][CH:15]=2)[N:8]=1)=O.[F:26][C:27]([F:40])([F:39])[S:28]([C:31]1[CH:32]=[C:33]([NH:37][NH2:38])[CH:34]=[CH:35][CH:36]=1)(=[O:30])=[O:29]>>[F:40][C:27]([F:39])([F:26])[S:28]([C:31]1[CH:32]=[C:33]([N:37]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][C:17]([O:20][C:21]([F:23])([F:22])[F:24])=[CH:16][CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:38]2)[CH:34]=[CH:35][CH:36]=1)(=[O:30])=[O:29]

Participants

3

Reactant 2

HCID 593700343-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-oneHCID 67422870HCID 67422870, compound

Product 1

HCID 59369968HCID 59369968, compound

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-8) and (3-trifluoromethanesulfonyl-phenyl)-hydrazine according to the method described for example 91. MS: M=531.1 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-6a0f53b7485e447d85113a7cb4619a9d
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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