HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Fluoro-4-hydrazinoquinoline → 1-(4-Difluoromethoxy-phenyl)-3-[2-(6-fluoro-quinolin-4-yl)-2H-pyrazol-3-yl]-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Fluoro-4-hydrazinoquinoline | HCID 17039615 | — |
| Reactant | 1-(4-Difluoromethoxy-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one | HCID 59369978 | — |
| Product | 1-(4-Difluoromethoxy-phenyl)-3-[2-(6-fluoro-quinolin-4-yl)-2H-pyrazol-3-yl]-1H-pyridazin-4-one | HCID 59370169 | — |
Reaction Steps
The product was obtained starting from 1-(4-Difluoromethoxy-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one (A-9) and (6-fluoro-quinolin-4-yl)-hydrazine according to the method described for example 91. MS: M=450.1 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-df943ba6fb034d1a854c60d15330cbbe |
| Source note | uspto-grants-2012_05 |