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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924635Generated: October 26, 2026

[3-(Trifluoromethoxy)phenyl]hydrazine → 1-(4-Difluoromethoxy-phenyl)-3-[2-(3-trifluoromethoxy-phenyl)-2H-pyrazol-3-yl]-1H-pyridazin-4-one

https://huagongshe.com/reaction/1924635

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[3-(Trifluoromethoxy)phenyl]hydrazineHCID 5194226—
Reactant1-(4-Difluoromethoxy-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-oneHCID 59369978—
Product1-(4-Difluoromethoxy-phenyl)-3-[2-(3-trifluoromethoxy-phenyl)-2H-pyrazol-3-yl]-1H-pyridazin-4-oneHCID 59369969—

Reaction Steps

The product was obtained starting from 1-(4-Difluoromethoxy-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one (A-9) and 3-trifluoromethoxy-phenylhydrazine according to the method described for example 91. MS: M=465.2 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-68635bda5574448ea9e705c867c1589e
Source noteuspto-grants-2012_05