HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(3-hydrazinylphenyl)acetamide → N-(3-{5-[4-Oxo-1-(4-trifluoromethoxy-phenyl)-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(3-hydrazinylphenyl)acetamide | HCID 45076296 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one | HCID 59370034 | — |
| Product | N-(3-{5-[4-Oxo-1-(4-trifluoromethoxy-phenyl)-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-phenyl)-acetamide | HCID 59370124 | — |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-8) and N-(3-hydrazino-phenyl)-acetamide according to the method described for example 91. MS: M=456.2 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-5f012b8486324163a15692575d346561 |
| Source note | uspto-grants-2012_05 |