HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Fluoro-4-hydrazinyl-2-methyl-quinoline → 3-[2-(6-Fluoro-2-methyl-quinolin-4-yl)-2H-pyrazol-3-yl]-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Fluoro-4-hydrazinyl-2-methyl-quinoline | HCID 493235 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one | HCID 59370123 | — |
| Product | 3-[2-(6-Fluoro-2-methyl-quinolin-4-yl)-2H-pyrazol-3-yl]-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one | HCID 59370103 | — |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and (6-fluoro-2-methyl-quinolin-4-yl)-hydrazine according to the method described for example 91. MS: M=482.2 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-9b4382d1d125480ab01e92316c95bcce |
| Source note | uspto-grants-2012_05 |