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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924649Generated: November 2, 2026

N-(3-hydrazinylphenyl)acetamide → N-(3-{5-[4-Oxo-1-(3-trifluoromethoxy-phenyl)-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-phenyl)-acetamide

https://huagongshe.com/reaction/1924649

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-hydrazinylphenyl)acetamideHCID 45076296—
Reactant3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-oneHCID 59370123—
ProductN-(3-{5-[4-Oxo-1-(3-trifluoromethoxy-phenyl)-1,4-dihydro-pyridazin-3-yl]-pyrazol-1-yl}-phenyl)-acetamideHCID 59370114—

Reaction Steps

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and N-(3-hydrazino-phenyl)-acetamide according to the method described for example 91. MS: M=456.2 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-4a9b95ae6fc14f04bc92d94cbaf5c6d8
Source noteuspto-grants-2012_05