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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924656Generated: October 30, 2026

4-Hydrazinoquinoline → 3-(2-Quinolin-4-yl-2H-pyrazol-3-yl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

https://huagongshe.com/reaction/1924656

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydrazinoquinolineHCID 7020411—
Reactant3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-oneHCID 59370034—
Product3-(2-Quinolin-4-yl-2H-pyrazol-3-yl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-oneHCID 46220472—

Reaction Steps

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-8) and quinolin-4-yl-hydrazine according to the method described for example 43. MS: M=450.1 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-f899b4bb8772440388d0d92cabb73765
Source noteuspto-grants-2012_05