Hydrazine, 1-naphthalenyl- → 1-(3-Bromo-phenyl)-3-(2-naphthalen-1-yl-2H-pyrazol-3-yl)-1H-pyridazin-4-one

HRID 1924659Notes

Reaction equation

HRID 1924659 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:13]=[CH:12][C:11](=[O:14])[C:10]([C:15](=O)/[CH:16]=[CH:17]/[N:18](C)C)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[C:22]1([NH:32]N)[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH:25]=[CH:24][CH:23]=1>>[Br:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:13]=[CH:12][C:11](=[O:14])[C:10]([C:15]3[N:32]([C:22]4[C:31]5[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=5)[CH:25]=[CH:24][CH:23]=4)[N:18]=[CH:17][CH:16]=3)=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 75240Hydrazine, 1-naphthalenyl-HCID 59370099HCID 59370099, compound

Product 1

HCID 593700971-(3-Bromo-phenyl)-3-(2-naphthalen-1-yl-2H-pyrazol-3-yl)-1H-pyridazin-4-one

Procedure

The product was obtained starting from 1-(3-Bromo-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one (A-18) and naphthalen-1-yl-hydrazine according to the method described for example 1. MS: M=443.2 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-a35bf17bae8e4f088a11b35c0cb9bbe8
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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