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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924664Generated: October 31, 2026

6-Fluoro-4-hydrazinyl-2-methyl-quinoline → 3-{3-[2-(6-Fluoro-2-methyl-quinolin-4-yl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-N,N-dimethyl-benzenesulfonamide

https://huagongshe.com/reaction/1924664

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Fluoro-4-hydrazinyl-2-methyl-quinolineHCID 493235—
Reactant3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamideHCID 59370163—
Product3-{3-[2-(6-Fluoro-2-methyl-quinolin-4-yl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-N,N-dimethyl-benzenesulfonamideHCID 59370091—

Reaction Steps

The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-N,N-dimethyl-benzenesulfonamide (A-12) and (6-fluoro-2-methyl-quinolin-4-yl)-hydrazine according to the method described for example 91.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-acb588e35189408dab38c8046f947e75
Source noteuspto-grants-2012_05