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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924666Generated: November 1, 2026

4-Hydrazinoquinoline → 1-(3-Methoxy-phenyl)-3-(2-quinolin-4-yl-2H-pyrazol-3-yl)-1H-pyridazin-4-one

https://huagongshe.com/reaction/1924666

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydrazinoquinolineHCID 7020411—
Reactant3-((E)-3-Dimethylamino-acryloyl)-1-(3-methoxy-phenyl)-1H-pyridazin-4-oneHCID 59369989—
Product1-(3-Methoxy-phenyl)-3-(2-quinolin-4-yl-2H-pyrazol-3-yl)-1H-pyridazin-4-oneHCID 59370159—

Reaction Steps

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methoxy-phenyl)-1H-pyridazin-4-one (A-5) and quinolin-4-yl-hydrazine according to the method described for example 91. MS: M=396.0 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-e39e9ace532b47b19bba0a788d4b0478
Source noteuspto-grants-2012_05