(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-hydrazine → 3-[2-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-2H-pyrazol-3-yl]-1-(3-methoxy-phenyl)-1H-pyridazin-4-one

HRID 1924671Notes

Reaction equation

HRID 1924671 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=2)[N:8]=1)=O.[O:23]1[C:28]2[CH:29]=[CH:30][C:31]([NH:33]N)=[CH:32][C:27]=2[O:26][CH2:25][CH2:24]1>>[O:23]1[C:28]2[CH:29]=[CH:30][C:31]([N:33]3[C:5]([C:7]4[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]5[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=5)[N:8]=4)=[CH:4][CH:3]=[N:2]3)=[CH:32][C:27]=2[O:26][CH2:25][CH2:24]1

Participants

3

Reactant 2

HCID 5164485(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-hydrazineHCID 593699893-((E)-3-Dimethylamino-acryloyl)-1-(3-methoxy-phenyl)-1H-pyridazin-4-one

Product 1

HCID 593700373-[2-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-2H-pyrazol-3-yl]-1-(3-methoxy-phenyl)-1H-pyridazin-4-one

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methoxy-phenyl)-1H-pyridazin-4-one (A-5) and (2,3-dihydro-benzo[1,4]dioxin-6-yl)-hydrazine according to the method described for example 91. MS: M=403.4 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-6b2b59296d9d47d796a313055778552f
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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